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Dr. Lewis is the Bird Dogs Chair in Translational Oncology at the University of Alberta in Edmonton, Alberta. As a scientist and serial entrepreneur, he pioneered the use of intravital imaging in the in vivo study of tumour cell invasion and metastasis to discover key targets for cancer therapeutics. Dr. Lewis also develops novel nanotechnology, nanoparticle drug delivery technologies, and imaging-based treatments for chronic diseases, such as aging and cancer, as well as for early detection of cancers. Dr. Lewis trained at The Scripps Research Institute and received a Ph.D. in biochemistry from the University of Victoria.
Over 321 books from 170 plus interviews over 5 years
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PODCAST INFO:
The Learning With Lowell show is a series for the everyday mammal. In this show we’ll learn about leadership, science, and people building their change into the world. The goal is to dig deeply into people who most of us wouldn’t normally ever get to hear. The Host of the show – Lowell Thompson- is a lifelong autodidact, serial problem solver, and founder of startups.
LINKS
Spotify: https://open.spotify.com/show/66eFLHQclKe5p3bMXsCTRH
RSS: https://www.learningwithlowell.com/feed/podcast/
Youtube: https://www.youtube.com/channel/UCzri06unR-lMXbl6sqWP_-Q
Youtube clips: https://www.youtube.com/channel/UC-B5x371AzTGgK-_q3U_KfA
Website: https://www.learningwithlowell.com/
John Lewis links
https://www.entospharma.com/about
https://ca.linkedin.com/in/john-lewis-29301614
nanosticsdx.com
entospharma.com
Timestamp / show notes
00:00 Intro
00:52 Multiple companies / Sleep / time management
02:55 Metastatic cancer treatment
05:40 Flamide / cancer
06:45 Michael Levin immortal cancer cells and cancer spreading
08:55 Covid parallel
09:55 Early detection / improving cancer survivability rates
12:20 Innovation and great science
15:45 Implementing metastatic research
17:40 FDA organ on a chip / cancer on a chip
19:00 Next generation nucleic acid platform
21:30 Covid and manhattan project acceleration
25:00 mRNA vs DNA based vaccine
27:35 2016 founding of Entos Pharmaceuticals
29:00 FQ barrel_master Political instability preventing clinical trial and continuing trials
30:45 Coup stopping clinical trial
31:55 FQ attofreak mitochondrial dysfunction in autoimmune diseases
34:55 Moments when things worked out
36:40 Personal expertise / superpowers
38:15 Currently learning / delivery platform to cells
40:14 Defining their platform
41:33 Targeting cancer and biophysics nanoparticles
43:20 Open source AI, ChatGPT, OpenAI, ML
45:10 Parallels from other companies
46:30 Assessing new technologies to add to business
49:45 Decision making for focus
51:50 End of 2030 to fight cancer
54:10 FDA approval and platform technology
55:15 Corpus of cancers
56:15 Discovering unknown cancers
57:15 FQ barrel_master Oisin’s cancer treatment from trials
58:15 Diverse populations for clinical research
59:45 Hiding cure for cancer
01:00:50 FQ barrel_master Oisin’s tech targets a Thymus or any other organ
01:02:30 FQ barrel_master considered transcribing for the diphtheria toxin
01:03:20 Future vision of companies – IPO, acquisition, etc
01:05:33 Partnerships
01:06:20 Advice for 25-35 year olds
01:07:51 Rare skill sets
01:08:50 Keeping investors happy
01:10:25 Differentiate real vs fake people
01:11:40 Strategy for hiring / question asking
01:13:50 Books!
01:16:30 DNA vs mRNA vaccine deliverability compared
01:18:50 Open source biotech / technology
01:20:21 Licensing in biotech
01:21:20 Exclusive vs non exclusive
01:21:55 Unanswered question
01:22:55 Orally bioavailable genetic medicine
01:24:55 Staying up to date with his work