Has Oisin discovered the next OZEMPIC? 4x Muscle, Living Longer & Healthier – Matthew Scholz 236

January 8, 2024

Matthew and Lowell discussed the development of a new DNA targeting intervention to clear senescent cells. They highlighted the unique approach of Oisin, which targets cells based on their transcriptional activity rather than their appearance or behavior. The conversation also touched on the challenges of DNA delivery, the potential for future adaptations to target new pathways, and the advantages of their non-viral vector. Matthew shared his journey into biotech, developing an app store for the human body, and the shift in the field’s perception of his idea. The conversation ended with a discussion on the potential of using machine learning and control in building therapies that would have been difficult in the past.

PODCAST INFO:

The Learning With Lowell show is a series for the everyday mammal. In this show we’ll learn about leadership, science, and people building their change into the world. The goal is to dig deeply into people who most of us wouldn’t normally ever get to hear. The Host of the show – Lowell Thompson- is a lifelong autodidact, serial problem solver, and founder of startups.

LINKS

Spotify: https://open.spotify.com/show/66eFLHQclKe5p3bMXsCTRH

RSS: https://www.learningwithlowell.com/feed/podcast/

Youtube: https://www.youtube.com/channel/UCzri06unR-lMXbl6sqWP_-Q

Youtube clips: https://www.youtube.com/channel/UC-B5x371AzTGgK-_q3U_KfA

Website: https://www.learningwithlowell.com

Matthew Scholz links

https://www.linkedin.com/in/matthewscholz
https://www.oisinbio.com/

Timestamps

01:30 DNA Targeting Intervention for Senescent Cells

10:00 Business Model and Teamwork in Biotech

16:00 Immune System App Store Conceptualization

19:00 Bio App Store Journey: From Skepticism to Acceptance

27:00 Team’s Journey: Overcoming Challenges, Securing Funding

36:00 Seed Rounds in Biotechnology: Simplified and Protective

39:00 Senescent Cell Therapies and Brain Health

47:00 Preclinical to Clinical Challenges and Animal Testing Concerns

53:00 Targeted Biological Research Challenges

57:00 Machine Learning in Therapy Development

1:00:00 Schwarzenegger Mice: Benefits and Risks in Therapy and Metabolic Health

1:10:00 Foundations, Research, and Synthetic Biology

1:15:00 Where He needs help

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