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Collin Yvès Ewald is a Swiss scientist investigating the molecular mechanisms of healthy aging. He is a molecular biologist and a professor at ETH Zurich, where he leads the Laboratory of Extracellular Matrix Regeneration
Over 321 books from 170 plus interviews over 5 years
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PODCAST INFO:
The Learning With Lowell show is a series for the everyday mammal. In this show we’ll learn about leadership, science, and people building their change into the world. The goal is to dig deeply into people who most of us wouldn’t normally ever get to hear. The Host of the show – Lowell Thompson- is a lifelong autodidact, serial problem solver, and founder of startups.
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Collin Ewald links
https://en.wikipedia.org/wiki/Collin_Y._Ewald
Concept figure of ECM and aging
https://doi.org/10.1159/000504295
C. elegans lifespan machine and microfluidics
https://doi.org/10.1016/j.isci.2022.103983
Matreotype = ECM composition and drug discovery
https://doi.org/10.1111/acel.13441
End of life intervention to double the lifespan
https://doi.org/10.7554/eLife.71335
AI and drug discovery
https://doi.org/10.3390/ijms24097850
Mechanotransduction and longevity
Every cell makes its own ECM
https://doi.org/10.1016/j.mbplus.2021.100069
“Here is the link to order the worms for doing the late-life DAF-2degron auxin-induced degradation. The C. elegans strain name is: RAF2181”
https://cgc.umn.edu/strain/RAF2181
Time stamps / Show notes
0:00:00 – Longevity and the Extracellular Matrix
0:08:13 – Rejuvenating the Extracellular Matrix
0:20:20 – Cell Differentiation and Theoretical Biology
0:29:19 – Machine Learning and Drug Discovery
0:33:35 – Machine Learning and Data Security
0:47:09 – Using C. Elegans for Lifespan Research
0:55:12 – Modeling Aging and Longevity
1:05:16 – Mechanotransduction and Oxen Degradation System
1:11:33 – Oxygen Treatment Doubles Worm Lifespan
1:15:59 – Rejuvenation and Aging in Biology
1:22:25 – Aging, Books, and Clinical Trials
1:30:38 – Collaborating in Science