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Dr. Björn Schumacher is the Principal Investigator and Chair for Genome Stability in Ageing and Disease at the Institute for Genome Stability in Aging and Disease. His research group uses the nematode worm Caenorhabditis elegans to understand the causal role of DNA damage in aging and disease.
Over 321 books from 170 plus interviews over 5 years
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PODCAST INFO:
The Learning With Lowell show is a series for the everyday mammal. In this show we’ll learn about leadership, science, and people building their change into the world. The goal is to dig deeply into people who most of us wouldn’t normally ever get to hear. The Host of the show – Lowell Thompson- is a lifelong autodidact, serial problem solver, and founder of startups.
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Website: https://www.learningwithlowell.com/
Björn Schumacher
https://www.cecad.uni-koeln.de/research/principal-investigators/prof-dr-bjoern-schumacher
Timestamps / chapters
00:00 START!
00:48 Research into DNA repair mechanisms
02:07 Deciding to pursue research
03:40 Passion in biology
06:40 Tools, tech, and mythology limits for longevity research
10:10 Best data to gather on humans
12:10 Mouth swap and more data
14:00 Blood donation and signing up for research
15:00 Access to the data
17:40 Places leading the world in research
20:35 Immortal germline how and why
24:30 DREAM complex downregulation functions
28:10 Regulating DREAM complex in humans
29:30 Academia to biotech startup transition
31:30 Timeline to startup
33:35 Humans and DREAM complex
34:40 Typical DNA damage
37:40 DanThePurple listener question on DDR and DREAM complex
40:15 Extensive of worm lifespan
40:40 Enough_Concentrate21 listener question DNA damage repair in young vs old populations
42:30 Axolotls, whales vs humans for regeneration and aging
45:25 Life expensive and healthspan increase for humans with his research applied to them
48:30 Single or multiple interventions with DNA damage repair
50:15 Capacity of his research
51:15 Help he needs
52:25 SENS and other partnerships
53:38 Amount needed to complete research
54:50 Grant money and research
56:40 100 year projects
57:58 25 to 35 year old advice for getting into longevity
01:00:10 Bad advice to avoid
01:02:20 Mark C fan question on AI and ML advances on longevity
01:04:50 Knowledge to save if we had to reset
01:05:30 Udhasudas fan question on radiation dose on humans
01:09:06 Shocking affect
01:10:50 Miscarriages
01:11:50 Regeneration of germ cells
01:13:15 Books!
01:14:20 Staying up to date with Bjorn’s work
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