Breakthroughs in Brain Rejuvenation, Longevity, and Tissue Replacement with Dr. Jean Hebert – 212

August 22, 2023

Join Jean Hebert, a leading expert in brain health, as he delves into the transformative potential of brain tissue replacement, brain computer interfaces, and their implications for reversing aging. In this comprehensive discussion, Jean shares insights on the science of brain restoration, the challenges and innovations in the field, and the broader implications of these technologies for the future of brain health and aging. Discover how modern science is pushing the boundaries of brain health and offering hope for a future where aging can be countered.

TLDR: The key idea of the video is that brain tissue replacement has the potential to restore brain function and reverse aging, and industry partnerships could accelerate its development.

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PODCAST INFO:

The Learning With Lowell show is a series for the everyday mammal. In this show we’ll learn about leadership, science, and people building their change into the world. The goal is to dig deeply into people who most of us wouldn’t normally ever get to hear. The Host of the show – Lowell Thompson- is a lifelong autodidact, serial problem solver, and founder of startups.

LINKS

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RSS: https://www.learningwithlowell.com/feed/podcast/

Youtube: https://www.youtube.com/channel/UCzri06unR-lMXbl6sqWP_-Q

Youtube clips: https://www.youtube.com/channel/UC-B5x371AzTGgK-_q3U_KfA

Website: https://www.learningwithlowell.com/

Jean Hebert links

Timestamps / Chapters

00:00 Brain computer interfaces vs rejuvenation for brain damage

02:02 Why choose brain aging?

06:08 Specificity of tissue replacement

09:00 Rough timeline and what’s left to develop

11:20 Jean Herbert’s role at a spun out company

12:20 Startup transition / production compared to academia 

14:00 Places to steal from

15:10 Amount needed to raise 

16:20 Jean Hebert Thesis compared to Michael Levin to generate tissue

18:40 Neuro Cortical precursor cell types to include vs not include 

21:10 Workhorse cells / Glial cells /precursor neurons 

22:30 Prevent Scarring during tissue replacements 

24:22 Suppressing immune system 

27:05 Mice the best model for this research

30:00 AI in lab or expectations to use / FAN Q

33:13 Using surgical robots

34:00 Micro glial engineering project explained

36:40 Alzhemers / diseases for micro glial project and tissue replacement 

38:00 Amyloid-beta aggregates relate to neurodegeneration FANQ

39:55 Replace the whole brain

42:30 Staging the replacement of the brain over time / process for replacement 

44:30 Microrobots / microsurgery option 

45:40 Mice model / adapting to intervention

48:18 Optimal time to apply the rejuvenation technology

51:40 Any other way to achieve the result hes going for outside of his approaches

54:00 Viewpoint on the role of the extracellular matrix (ECM) in the damage that needs to be addressed (FANQ)

57:30 Thermodynamic Theory of Aging (FAN Q)

59:59 Other startups being spun out of lab FANQ

01:01:00 People he is on the lookout for

01:02:24 Building in Midwest or staying in NYC

01:03:00 Book recommendations 

01:03:30 how to get involved 

01:05:40 Self taught people / coders/ etc finding a way to be helpful

01:07:00 Non surgical methods of tissue replacement FANq

01:09:30 Layering the cells for replacement

01:11:00 People to focus on in the aging / longevity 

01:15:00 Brain in a jar

#tissuereplacement #longevity #rejuvenation

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